Prostate Surgery

By prostate Doc at 29 September, 2008, 5:44 pm

Prostatectomy for Cure
Selection of candidates suitable for surgery is based on the natural history of prostate cancer, its Gleason score, the life expectancy of the candidate, and consideration of morbidity from the operation. The best candidates for total prostatectomy are those likely to benefit from it, and therefore, they should be young enough to [...]

Chemotherapy of Hormone Refractory Disease

By prostate Doc at 23 September, 2008, 7:43 pm

Historically, hormone refractory prostate cancer has been viewed as a condition minimally responsive to cytotoxic agents. This view is largely based on data generated before the mid-1990s using single agents or combinations of drugs. Doxorubicin, cyclophosphamide, vinblastine, cisplatin, fluorouracil, mitoxantrone, and estramustine have all been shown to have objective response rates <15%.