Archive for September, 2008
Prostate Surgery
By prostate Doc at 29 September, 2008, 5:44 pm
Prostatectomy for Cure
Selection of candidates suitable for surgery is based on the natural history of prostate cancer, its Gleason score, the life expectancy of the candidate, and consideration of morbidity from the operation. The best candidates for total prostatectomy are those likely to benefit from it, and therefore, they should be young enough to [...]
Chemotherapy of Hormone Refractory Disease
By prostate Doc at 23 September, 2008, 7:43 pm
Historically, hormone refractory prostate cancer has been viewed as a condition minimally responsive to cytotoxic agents. This view is largely based on data generated before the mid-1990s using single agents or combinations of drugs. Doxorubicin, cyclophosphamide, vinblastine, cisplatin, fluorouracil, mitoxantrone, and estramustine have all been shown to have objective response rates <15%.
Read More >>Prostate Treatment
By prostate Doc at 22 September, 2008, 6:41 pm
While patients may have a difficult time accepting the diagnosis of prostate cancer, the decision regarding treatment is often the most difficult part of the process.
Read More >>Antiandrogen Withdrawal : Prostate
By prostate Doc at 16 September, 2008, 3:55 pm
Withdrawal of antiandrogens at progression is associated with a decline in PSA and improvement in clinical symptoms in approximately 20% of patients. The median duration of response is three to five months and is seen four weeks from with- drawal of flutamide.
Read More >>Secondary Hormonal Therapies : Prostate
By prostate Doc at 16 September, 2008, 8:28 am
Despite the high initial response to hormonal therapy, virtually all patients with metastatic disease progress. The median time to progression is 16-18 months. When progression occurs, primary androgen deprivation should be maintained.
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